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Our mission is to redefine the very fabric of molecule development, propelling us into a new era where biotechnology is created in ways never before imagined.

Revolutionizing Molecule Discovery through Generative Biology!

We're at the forefront of cutting-edge technology, combining machine learning, biological engineering, and biotechnology to pioneer Generative Biology—an exciting new approach that revolutionizes how medicines are developed.

Cellertz Bio, a therapeutics company:

Single Cell Multi Omics

Machine Learning

Fusion of scientific disciplines

for

Enhanced R&D Productivity

Biotechnology

Data-driven, rationally designed cell therapies

Our pioneering methodology seamlessly combines advanced computational approach and rigorous experimental techniques to propel the development of the next frontier in cell therapies to treat cancer.

 

By exerting meticulous control over gene regulatory networks that govern crucial cell behaviors, we aspire to revolutionize the field of disease treatment.

 

Our primary objective revolves around identifying the optimal gene targets to modulate, allowing us to unlock the full potential of cell therapy and achieve unprecedented therapeutic outcomes.

Unleashing the Power of Gene Regulation

Revolutionizing Molecule Discovery and Development

OUR TECHNOLOGY PLATFORM:

Innovating Breakthrough Therapies through Multiscale Biology Integration

Our Discovery Platform empowers us to identify crucial biological patterns within vast biomedical datasets. Leveraging proprietary algorithms for multi-modal single-cell analysis, we reconstruct developmental processes, gene regulatory networks, signaling pathways, and gene expression programs linked to the onset, progression, stem cell differentiation, and development of diseases.

01 DISCOVERY PLATFORM

Our Generative Biology Platform, CODONSCOPE, employs cutting-edge deep learning techniques to generate novel molecules with precise properties, accelerating cell therapy and drug discovery. These molecules target genes and pathways identified in our Gene Discovery platform, offering enhanced control over gene expression in specific cell types.

02 GENERATIVE BIOLOGY PLATFORM (CodonScope)

With our Cell Therapy Platform, we harness the power of our Generative Biology and Gene Discovery platforms to pioneer the next generation of intelligent, living biotherapeutics. Our focus initially centers on combating cancer, utilizing cell-based treatments as a transformative alternative to traditional drugs.

03 CELL THERAPY PLATFORM

Founder & Scientific Advisor

Edroaldo Lummertz da Rocha, PhD

Dr. Lummertz da Rocha’s research at the intersection of biology, computational biology and artificial intelligence has contributed to advance the fields of stem cell biology and engineering as well as cancer research. Dr. Lummertz da Rocha trained in prestigious universities, hospitals and research institutions, such as the Wyss Institute for Biologically Inspired Engineering at Harvard University, Mayo Clinic, Boston Children’s Hospital and Harvard Medical School. Dr. Lummertz da Rocha is an Assistant Professor at Federal University of Santa Catarina and Affiliate Faculty of Dell Medical School at the University of Texas in Austin. He has secured funding from the National Institutes of Health, USA, The State of Santa Catarina Research and Innovation Support Foundation (FAPESC) and the Serrapilheira Institute, Brazil, to support his laboratory’s research on hematopoiesis and cancer metastasis at the intersection with biomedical data science.

Executive Chair - Cellertz Bio

Claudia Mitchell, PhD

Claudia Mitchell is the Chair of Cellertz and the CEO of Savantia, a biotech strategy and consulting firm. She brings over 20 years of leadership experience in biopharma across the US, Europe, and Asia. Claudia is also the Chair of Cellerys and a member of the Board of Directors of Gubra and Coave Therapeutics. Previously, she served as Senior Vice President of Portfolio Strategy at Astellas Pharma in Tokyo. Prior to that, she was CEO and co-founder of Universal Cells, a US-based biotech company acquired in 2019, and co-founder and Chief Scientific Officer of Halo-Bio RNAi Therapeutics. Earlier in her career, she held research leadership roles at INSERM in Paris and at the LGMD2I Research Fund, a US-based nonprofit. Claudia holds a PhD in Molecular Biology from the University of Paris and an MBA in International Management from École des Ponts Business School. In 2018, she was named EY Entrepreneur of the Year in Life Sciences for the Pacific Northwest, USA.

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Board Member - Cellertz Bio

Dr. Rogerio Vivaldi Coelho

Rogério Vivaldi Coelho, M.D., M.B.A., retired as the president, Chief Executive Officer and a Director of Sigilon Therapeutics, Inc. in December 2023. Prior to joining Sigilon, Dr. Vivaldi served as Executive Vice President and Chief Global Therapeutics Officer at Bioverativ Inc. from 2016 to 2018. Prior to that Dr. Vivaldi served as Chief Commercial Officer at Spark Therapeutics, Inc. Earlier, he held several positions of increasing responsibility over a 20-year career at Genzyme, most recently serving as the head of the company’s rare disease business, president of both the rare disease business and the renal & endocrine group, and as Senior Vice President and General Manager of its Latin America group. During his time at Genzyme, he led the successful approval of more than 15 orphan products in more than 20 countries. Dr. Vivaldi serves as a member of the board of directors and science and technology committee of Viatris Inc., a publicly traded healthcare company. Rogério also serves as a Board member of Crinetics Pharmaceuticals, a publicly traded company and as a Chairman of the BoD of Vesper Biotechnologies, the venture builder company that co-founded Cellertz alongside Dr. Lummertz. 

Rogerio earned a medical degree from the Universidade do Rio de Janeiro, after which he completed a residency in endocrinology at the Universidade do Estado do Rio de Janeiro and a fellowship at Mount Sinai Hospital Center in New York in the department of genetics, focusing on Gaucher disease. He later became the first physician in Brazil to treat Gaucher disease using enzyme replacement therapy. In addition, Dr. Vivaldi holds an M.B.A. degree from COPPEAD, Universidade Federal do Rio de Janeiro. Dr. Vivaldi’s experience as an executive officer in the life sciences industry and his extensive pharmaceutical commercialization and marketing experience with several different companies contributes greatly to Cellertz’s Board of Directors.

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Board Member - Cellertz Bio

Jonas Sister

Jonas Sister is an economist with over 25 years of experience in venture capital, private equity, and M&A, with a proven track record in investment strategy, governance, and portfolio value creation.

 

He is a Co-Founding Partner and CFO at Vesper Biotechnologies, a venture builder pioneering biotech investments from Brazil, which co-founded Cellertz Bio.

Before founding Vesper, Jonas was a Partner at BRZ Investimentos, where he led investments and served on the boards of several portfolio companies during a ten-year tenure. Earlier in his career, he held roles in Strategic Planning, FP&A, and M&A at Votorantim, one of Brazil’s leading industrial conglomerates.

 

Jonas began his career at Nexxy Capital, a pioneer in Brazilian venture capital and part of the Exxel Group, then the largest private equity platform in Latin America.

 

He holds a degree in Economics from the University of São Paulo (USP), a specialization in International Management from Hogeschool Haarlem (Netherlands), and an MBA from Insper (Brazil).

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Our Advisory Team

Our advisory team unites pioneering minds from science and industry who share a vision of transforming discoveries into life-changing innovations. Their insight and experience guide our path from bold ideas to real-world impact.

Computational Chemist

Felipe Silveira de Souza Schneider, PhD

Felipe is a skilled computational chemist with expertise in physical, quantum, and computational chemistry. He holds a Master's degree in physical chemistry and has recently completed his PhD in computational chemistry at the Federal University of Santa Catarina. Felipe has made significant contributions in the field, particularly through the development of a state-of-the-art tool that predicts chemical kinetic profiles of reaction mechanisms using first-principle quantum chemistry calculations exclusively. In addition to his background in chemistry, he is also a skilled software developer proficient in multiple programming languages, including Python, Julia, and Rust. His current research interests span across artificial intelligence and molecular design. With his diverse skill set and unwavering passion for scientific innovation, Felipe is dedicated to pushing the boundaries of knowledge.

Cellular and Molecular Biologist

Barbara P. Coelho, PhD

Dr. Barbara P. Coelho is a cellular and molecular biologist expert in cancer and stem cell research. She earned both her Master's and PhD degrees in Biochemistry from the Federal University of Rio Grande do Sul. Her extensive expertise encompasses diverse research projects involving complex cellular models, such as induced pluripotent stem cells (iPSCs) and organoids, which were developed during her postdoctoral fellow at the University of Sao Paulo. Passionate about deciphering intricate scientific challenges, Bárbara thrives on the complexities of her field. She is dedicated to making impactful contributions to cancer therapy research.

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Data Scientist

Gabriela Luiz, PhD

Bioinformatician expert on NGS data analysis and development of complex pipelines. She has extensive experience in omics approaches to study parasite-host relationship and worked on several genomic and transcriptomic projects, extracting information from data using bioinformatics analyzes in Perl, R, Bash and Python languages. She also was Statistics professor for Biological Sciences and Agronomy courses and in her postdoctoral studies, she developed an integrative analysis of hematopoietic stem cell atlas using single cell transcriptomic data.

Our Scientific Team

Working at the forefront of cutting-edge research and development, our team is dedicated to pushing the boundaries of scientific discovery.

 

We embrace the challenges of developing novel therapies and strive to translate our collective knowledge and skills into groundbreaking solutions that have the potential to transform lives.

Selected Publications

CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development

Nat Cell Biol. 2022 Apr.

Lifelong multilineage contribution by embryonic-born blood progenitors

Nature 2022

EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity

Cell Stem Cell 2022

LIN28B alters ribosomal dynamics to promote metastasis in MYCN-driven malignancy

JCI 2021

The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia

JEM 2019

Reconstruction of complex single-cell trajectories using CellRouter

Nature 2018 March

Haematopoietic stem and progenitor cells from human pluripotent stem cells

Nature 2017

NetDecoder: a network biology platform that decodes context-specific biological networks and gene activities

Nucleic Acids Res 2016

CellNet: Network Biology Applied to Stem Cell Engineering

Cell 2014

VIEW ALL PUBLICATIONS

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